{"id":500,"date":"2022-01-07T12:50:24","date_gmt":"2022-01-07T15:50:24","guid":{"rendered":"https:\/\/www.farmaciaevidence.com.br\/ciencia-pesquisa\/?p=500"},"modified":"2022-01-11T09:53:40","modified_gmt":"2022-01-11T12:53:40","slug":"smart-drugs-i-bacopa-monnieri-e-centella-asiatica","status":"publish","type":"post","link":"https:\/\/www.farmaciaevidence.com.br\/ciencia-pesquisa\/smart-drugs-i-bacopa-monnieri-e-centella-asiatica\/","title":{"rendered":"Smart drugs I &#8211; Bacopa Monnieri e Centella asiatica"},"content":{"rendered":"<p><i><span style=\"font-weight: 400;\">Bacopa Monnieri e Centella asiatica<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">Os nootr\u00f3picos costumam ser chamados de &#8220;<\/span><i><span style=\"font-weight: 400;\">smart drugs<\/span><\/i><span style=\"font-weight: 400;\">&#8221; (drogas inteligentes). Eles aumentam a velocidade de processamento do c\u00e9rebro, o aprendizado e o estado de alerta. Muitos nootr\u00f3picos usados \u200b\u200bhoje s\u00e3o medicamentos off-label que podem ter efeitos estimulantes indesejados.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Aqueles que preferem uma abordagem mais tranquila podem considerar nootr\u00f3picos \u00e0 base de plantas que demonstraram propriedades de aprimoramento cognitivo, os quais alguns ser\u00e3o abordados nesse artigo.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Demonstrou-se que esses extratos de plantas estudados clinicamente aumentam a mem\u00f3ria, aumentam a velocidade de processamento do c\u00e9rebro e melhoram a concentra\u00e7\u00e3o e o estado de alerta.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">O que s\u00e3o Nootr\u00f3picos?<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Os nootr\u00f3picos s\u00e3o diferentes dos compostos que protegem contra o envelhecimento do c\u00e9rebro ou decl\u00ednio cognitivo. Eles aumentam rapidamente o desempenho cognitivo, a velocidade de processamento do c\u00e9rebro, a agilidade mental e a aten\u00e7\u00e3o em adultos saud\u00e1veis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Eles podem conseguir isso aumentando o fluxo sangu\u00edneo para o c\u00e9rebro, combatendo a inflama\u00e7\u00e3o, modulando os n\u00edveis de neurotransmissores e aumentando o n\u00famero ou a efic\u00e1cia das sinapses (que permitem que os neur\u00f4nios se comuniquem).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Os cientistas identificaram compostos \u00e0 base de plantas mostrados em estudos humanos para melhorar a fun\u00e7\u00e3o cognitiva, velocidade de processamento e mem\u00f3ria.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><i><span style=\"font-weight: 400;\">Bacopa Monnieri<\/span><\/i><span style=\"font-weight: 400;\"> melhora a cogni\u00e7\u00e3o<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400;\">Bacopa monnieri<\/span><\/i><span style=\"font-weight: 400;\"> \u00e9 uma erva tradicionalmente usada na medicina ayurv\u00e9dica para tratar inflama\u00e7\u00e3o, dor, asma e dem\u00eancia. Textos antigos que datam do s\u00e9culo VI indicam que a Bacopa<\/span><i><span style=\"font-weight: 400;\"> monnieri<\/span><\/i><span style=\"font-weight: 400;\"> era usada para melhorar a mem\u00f3ria e agu\u00e7ar o intelecto.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Estudos cl\u00ednicos sugerem que a Bacopa<\/span><i><span style=\"font-weight: 400;\"> monnieri<\/span><\/i><span style=\"font-weight: 400;\"> pode melhorar o desempenho cognitivo em jovens e idosos saud\u00e1veis. Esses estudos indicam que os extratos de <\/span><i><span style=\"font-weight: 400;\">Bacopa monnieri<\/span><\/i><span style=\"font-weight: 400;\"> podem melhorar:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aquisi\u00e7\u00e3o de novas mem\u00f3rias;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Capacidade de reter e relembrar mem\u00f3rias;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Capacidade de manter a aten\u00e7\u00e3o e velocidade de aten\u00e7\u00e3o;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Taxa de aprendizagem;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mem\u00f3ria de trabalho;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Velocidade de processamento da informa\u00e7\u00e3o.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Um estudo humano descobriu que a ingest\u00e3o di\u00e1ria de extrato de <\/span><i><span style=\"font-weight: 400;\">Bacopa monnieri<\/span><\/i><span style=\"font-weight: 400;\"> por 12 semanas levou a uma melhora na mem\u00f3ria de trabalho (a capacidade de armazenar e usar informa\u00e7\u00f5es de curto prazo). As medi\u00e7\u00f5es da atividade cerebral mostraram que aqueles que tomaram <\/span><i><span style=\"font-weight: 400;\">Bacopa<\/span><\/i><span style=\"font-weight: 400;\"> tiveram um in\u00edcio mais r\u00e1pido dos padr\u00f5es de atividade associados \u00e0 aten\u00e7\u00e3o e ao processamento de informa\u00e7\u00f5es.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">O uso de <\/span><i><span style=\"font-weight: 400;\">Bacopa monnieri<\/span><\/i><span style=\"font-weight: 400;\"> tamb\u00e9m resultou em um <\/span><i><span style=\"font-weight: 400;\">decl\u00ednio<\/span><\/i><span style=\"font-weight: 400;\"> na atividade da enzima acetilcolinesterase. Essa enzima decomp\u00f5e o neurotransmissor acetilcolina, que est\u00e1 envolvido na mem\u00f3ria e na aten\u00e7\u00e3o. Experimentos de laborat\u00f3rio sugerem que <\/span><i><span style=\"font-weight: 400;\">Bacopa monnieri<\/span><\/i><span style=\"font-weight: 400;\"> tamb\u00e9m pode melhorar a fun\u00e7\u00e3o cognitiva por:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gerar novas c\u00e9lulas nervosas no hipocampo, 15 uma regi\u00e3o do c\u00e9rebro que desempenha um papel cr\u00edtico na aprendizagem e na mem\u00f3ria,<\/span><\/li>\n<\/ul>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aumentando a ramifica\u00e7\u00e3o e o comprimento dos dendritos (extens\u00f5es de c\u00e9lulas nervosas que recebem sinais de outras c\u00e9lulas nervosas),<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Melhorando o fluxo sangu\u00edneo cerebral,\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Inibindo a libera\u00e7\u00e3o de citocinas inflamat\u00f3rias e bloqueando enzimas envolvidas na inflama\u00e7\u00e3o,<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Modulando a produ\u00e7\u00e3o de neurotransmissores<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Melhora da atividade e dos n\u00edveis de enzimas e fatores de crescimento do nervo que est\u00e3o envolvidos na manuten\u00e7\u00e3o e cria\u00e7\u00e3o de novas sinapses.<\/span><\/li>\n<\/ol>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><i><span style=\"font-weight: 400;\">Centella asiatica<\/span><\/i><span style=\"font-weight: 400;\"> aumenta a fun\u00e7\u00e3o cerebral<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Gotu kola (<\/span><i><span style=\"font-weight: 400;\">Centella asiatica<\/span><\/i><span style=\"font-weight: 400;\">) \u00e9 uma planta com flor nativa da \u00c1sia. H\u00e1 muito tempo \u00e9 usado na medicina ayurv\u00e9dica para aumentar a mem\u00f3ria e a cogni\u00e7\u00e3o. Estudos cl\u00ednicos sugerem que a gotu kola pode melhorar o funcionamento cognitivo em adultos saud\u00e1veis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Um estudo com adultos de 35 a 50 anos mostrou que a ingest\u00e3o de gotu kola diariamente por dois meses melhorou o desempenho cognitivo, incluindo a recupera\u00e7\u00e3o de mem\u00f3rias e velocidade de processamento de informa\u00e7\u00f5es.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Em outro estudo, a ingest\u00e3o di\u00e1ria de extrato de cola de gotu por dois meses melhorou o tempo de rea\u00e7\u00e3o e a precis\u00e3o da mem\u00f3ria de trabalho em idosos saud\u00e1veis. Os pesquisadores tamb\u00e9m descobriram um aumento na atividade cerebral associada \u00e0 aten\u00e7\u00e3o durante uma tarefa cognitiva.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Estudos em animais confirmam que a gotu kola pode aumentar o n\u00famero de sinapses, reduzir o estresse oxidativo e melhorar a fun\u00e7\u00e3o das mitoc\u00f4ndrias produtoras de energia no hipocampo. O tratamento com extrato de gotu tamb\u00e9m estimulou o crescimento e a matura\u00e7\u00e3o das c\u00e9lulas nervosas e a forma\u00e7\u00e3o de sinapses em culturas de laborat\u00f3rio de c\u00e9lulas nervosas do hipocampo de rato.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Como o <\/span><i><span style=\"font-weight: 400;\">Bacopa<\/span><\/i><span style=\"font-weight: 400;\">, a <\/span><i><span style=\"font-weight: 400;\">Centella asiatica<\/span><\/i><span style=\"font-weight: 400;\"> aumenta o alongamento e a ramifica\u00e7\u00e3o dos dendritos no hipocampo e na am\u00edgdala em ratos adultos. Essas mudan\u00e7as est\u00e3o associadas a melhorias no aprendizado e na mem\u00f3ria.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Refer\u00eancias<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Life Extension. Dispon\u00edvel em &lt;https:\/\/www.lifeextension.com\/magazine\/2021\/12\/brain-speed-learning-retention&gt; Acesso: Novembro, 2021.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vollala VR, Upadhya S, Nayak S. Enhanced dendritic arborization of hippocampal CA3 neurons by Bacopa monniera extract treatment in adult rats. <\/span><i><span style=\"font-weight: 400;\">Rom J Morphol Embryol. <\/span><\/i><span style=\"font-weight: 400;\">2011;52(3):879-86.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nemetchek MD, Stierle AA, Stierle DB, et al. The Ayurvedic plant Bacopa monnieri inhibits inflammatory pathways in the brain. <\/span><i><span style=\"font-weight: 400;\">J Ethnopharmacol. <\/span><\/i><span style=\"font-weight: 400;\">2017 Feb 2;197:92-100.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aguiar S, Borowski T. 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Results of a randomized, placebo-controlled, double-blind trial. <\/span><i><span style=\"font-weight: 400;\">J Altern Complement Med. <\/span><\/i><span style=\"font-weight: 400;\">2010 Jul;16(7):753-9.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Peth-Nui T, Wattanathorn J, Muchimapura S, et al. Effects of 12-Week Bacopa monnieri Consumption on Attention, Cognitive Processing, Working Memory, and Functions of Both Cholinergic and Monoaminergic Systems in Healthy Elderly Volunteers. <\/span><i><span style=\"font-weight: 400;\">Evid Based Complement Alternat Med.<\/span><\/i><span style=\"font-weight: 400;\"> 2012;2012:606424.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Raghav S, Singh H, Dalal PK, et al. 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Efficacy of Standardized Extract of Bacopa monnieri (Bacognize(R)) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial. <\/span><i><span style=\"font-weight: 400;\">Evid Based Complement Alternat Med. <\/span><\/i><span style=\"font-weight: 400;\">2016 2016\/10\/10;2016:4103423.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Available at: <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539735\/\"><span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539735\/<\/span><\/a><span style=\"font-weight: 400;\">. Accessed September 23, 2021.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kwon HJ, Jung HY, Hahn KR, et al. Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus. <\/span><i><span style=\"font-weight: 400;\">Lab Anim Res. <\/span><\/i><span style=\"font-weight: 400;\">2018 Dec;34(4):239-47.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bruel-Jungerman E, Rampon C, Laroche S. Adult hippocampal neurogenesis, synaptic plasticity and memory: facts and hypotheses. <\/span><i><span style=\"font-weight: 400;\">Rev Neurosci. <\/span><\/i><span style=\"font-weight: 400;\">2007;18(2):93-114.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vollala VR, Upadhya S, Nayak S. Enhancement of basolateral amygdaloid neuronal dendritic arborization following Bacopa monniera extract treatment in adult rats. <\/span><i><span style=\"font-weight: 400;\">Clinics (Sao Paulo). <\/span><\/i><span style=\"font-weight: 400;\">2011;66(4):663-71.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hermans EJ, Battaglia FP, Atsak P, et al. How the amygdala affects emotional memory by altering brain network properties. <\/span><i><span style=\"font-weight: 400;\">Neurobiol Learn Mem. <\/span><\/i><span style=\"font-weight: 400;\">2014 Jul;112:2-16.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kamkaew N, Norman Scholfield C, Ingkaninan K, et al. Bacopa monnieri increases cerebral blood flow in rat independent of blood pressure. <\/span><i><span style=\"font-weight: 400;\">Phytother Res. <\/span><\/i><span style=\"font-weight: 400;\">2013 Jan;27(1):135-8.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Saini N, Singh D, Sandhir R. Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action. <\/span><i><span style=\"font-weight: 400;\">Metab Brain Dis. <\/span><\/i><span style=\"font-weight: 400;\">2019 Apr;34(2):505-18.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Charles PD, Ambigapathy G, Geraldine P, et al. Bacopa monniera leaf extract up-regulates tryptophan hydroxylase (TPH2) and serotonin transporter (SERT) expression: implications in memory formation. <\/span><i><span style=\"font-weight: 400;\">J Ethnopharmacol. <\/span><\/i><span style=\"font-weight: 400;\">2011 Mar 8;134(1):55-61.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Preethi J, Singh HK, Charles PD, et al. Participation of microRNA 124-CREB pathway: a parallel memory enhancing mechanism of standardised extract of Bacopa monniera (BESEB CDRI-08). <\/span><i><span style=\"font-weight: 400;\">Neurochem Res. <\/span><\/i><span style=\"font-weight: 400;\">2012 Oct;37(10):2167-77.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">McPhee GM, Downey LA, Noble A, et al. Cognitive training and Bacopa monnieri: Evidence for a combined intervention to alleviate age associated cognitive decline. <\/span><i><span style=\"font-weight: 400;\">Med Hypotheses. <\/span><\/i><span style=\"font-weight: 400;\">2016 Oct;95:71-6.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sabaragamuwa R, Perera CO, Fedrizzi B. Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy ageing. <\/span><i><span style=\"font-weight: 400;\">Trends in Food Science &amp; Technology. <\/span><\/i><span style=\"font-weight: 400;\">2018;79:88-97.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Parker C. Centella asiatica (Asiatic pennywort). <\/span><i><span style=\"font-weight: 400;\">Invasive Species Compendium. <\/span><\/i><span style=\"font-weight: 400;\">2014.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wattanathorn J, Mator L, Muchimapura S, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. <\/span><i><span style=\"font-weight: 400;\">J Ethnopharmacol. <\/span><\/i><span style=\"font-weight: 400;\">2008 Mar 5;116(2):325-32.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dev RDO, Mohamed S, Hambali Z, et al. Comparison on cognitive effects of Centella asiatica in healthy middle age female and male volunteers. <\/span><i><span style=\"font-weight: 400;\">European Journal of Scientific Research. <\/span><\/i><span style=\"font-weight: 400;\">2009;31(4):553-65.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gray NE, Harris CJ, Quinn JF, et al. Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice. <\/span><i><span style=\"font-weight: 400;\">J Ethnopharmacol. <\/span><\/i><span style=\"font-weight: 400;\">2016 Mar 2;180:78-86.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gray NE, Zweig JA, Caruso M, et al. Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice. <\/span><i><span style=\"font-weight: 400;\">Brain Behav. <\/span><\/i><span style=\"font-weight: 400;\">2018 Jul;8(7):e01024.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hannan MA, Haque MN, Munni YA, et al. Centella asiatica promotes early differentiation, axodendritic maturation and synaptic formation in primary hippocampal neurons. <\/span><i><span style=\"font-weight: 400;\">Neurochem Int. <\/span><\/i><span style=\"font-weight: 400;\">2021 Mar;144:104957.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mohandas Rao KG, Rao MS, Rao GS. Evaluation of amygdaloid neuronal dendritic arborization enhancing effect of Centella asiatica (Linn) fresh leaf extract in adult rats. <\/span><i><span style=\"font-weight: 400;\">Chin J Integr Med. <\/span><\/i><span style=\"font-weight: 400;\">2012 Dec 3.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mohandas Rao KG, Muddanna Rao S, Gurumadhva Rao S. Enhancement of Amygdaloid Neuronal Dendritic Arborization by Fresh Leaf Juice of Centella asiatica (Linn) During Growth Spurt Period in Rats. <\/span><i><span style=\"font-weight: 400;\">Evid Based Complement Alternat Med. <\/span><\/i><span style=\"font-weight: 400;\">2009 Jun;6(2):203-10.<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Bacopa Monnieri e Centella asiatica Os nootr\u00f3picos costumam ser chamados de &#8220;smart drugs&#8221; (drogas inteligentes). Eles aumentam a velocidade de processamento do c\u00e9rebro, o aprendizado e o estado de alerta. Muitos nootr\u00f3picos usados \u200b\u200bhoje s\u00e3o medicamentos off-label que podem ter efeitos estimulantes indesejados. Aqueles que preferem uma abordagem mais tranquila podem considerar nootr\u00f3picos \u00e0 base [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":512,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[63,64,44,55,61,42,38,62],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v15.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Smart drugs I - Bacopa Monnieri e Centella asiatica - Evidence - Ci\u00eancia e Pesquisa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.farmaciaevidence.com.br\/ciencia-pesquisa\/smart-drugs-i-bacopa-monnieri-e-centella-asiatica\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Smart drugs I - Bacopa Monnieri e Centella asiatica - Evidence - Ci\u00eancia e Pesquisa\" \/>\n<meta property=\"og:description\" content=\"Bacopa Monnieri e Centella asiatica Os nootr\u00f3picos costumam ser chamados de &#8220;smart drugs&#8221; (drogas inteligentes). Eles aumentam a velocidade de processamento do c\u00e9rebro, o aprendizado e o estado de alerta. Muitos nootr\u00f3picos usados \u200b\u200bhoje s\u00e3o medicamentos off-label que podem ter efeitos estimulantes indesejados. 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